Synonyms:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-nonyloxy)-8-oxooctyl)amino)octanoate
辛酸七烷-9-基 8-(2-羥乙基)(8-壬氧基)-8-氧辛基)氨基酯
1-Octylnonyl 8-[(2-hydroxyethyl)[8-(nonyloxy)-8-oxooctyl]amino]octanoate
1-辛(xin)基(ji)壬基(ji)8-[(2-羥乙基(ji))[8-(壬氧(yang)基(ji))-8-氧(yang)辛(xin)基(ji)]氨基(ji)]辛(xin)酸酯

分子式: C44H87NO5
分子量: 710.17
Storage condition: 2 years -20°C Powder, 2 weeks 4°C in DMSO,6 months -80°C in DMSO

新型可電離氨基(ji)(ji)脂質(zhi)，用于形(xing)成納米脂質(zhi)遞送(song)(song)系統LNPs，遞送(song)(song)mRNA核(he)酸藥(yao)(yao)物(wu)（如新冠疫(yi)苗，基(ji)(ji)因藥(yao)(yao)物(wu)等）。可在嚙齒動物(wu)和靈長類(lei)動物(wu)模型中提供有效的 mRNA 遞送(song)(song)，顯示出最(zui)佳(jia)的藥(yao)(yao)代動力(li)學和無毒(du)副(fu)作(zuo)用。